Every day the two kidneys filter about 180 litres of fluid and reabsorb nearly all of it, leaving only some 1.5 litres of concentrated urine. As blood pressure rises and falls the glomerular filtration rate moves with it, since pressure is what forces plasma through the capillary tuft inside Bowman's capsule. Chronic kidney disease drops filtration to roughly three tenths of normal; a stone blocks the urine flow and backs up the tract above it.
Every day the two kidneys filter about 180 litres of fluid and reabsorb nearly all of it, leaving only some 1.5 litres of concentrated urine. As blood pressure rises and falls the glomerular filtration rate moves with it, since pressure is what forces plasma through the capillary tuft inside Bowman's capsule. Chronic kidney disease drops filtration to roughly three tenths of normal; a stone blocks the urine flow and backs up the tract above it.
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