Neuron & Synapse · Human Body

NEURON & SYNAPSE SIMULATION

A neuron cannot speak softly or loudly: below threshold it stays silent, and past −55 mV it fires a spike identical to every one before it. Once the stimulus crosses threshold the membrane swings from −70 to +40 mV and repolarises, while the impulse leaps from one node of Ranvier to the next. With the myelin gone that leap disappears as conduction stalls; under botulinum toxin the impulse still reaches the terminal, but the synaptic vesicles never release their transmitter.

▸ Building the neuron: soma · dendrites · axon…

▸ Wrapping the myelin sheath + nodes of Ranvier

▸ Loading Na⁺ / K⁺ channels into the membrane

▸ Calibrating resting potential −70 mV

▸ Ready — Online. ✅

Membrane potential

🧠 Đang nghỉ

−70 resting · −55 threshold · +40 peak

Potential (Vm)—

Phase—

Firing rate—

Conduction speed—

Spikes fired—

Note

Inputs sum at the soma; crossing the −55 mV threshold → fires an action potential under the “all-or-none” rule. The myelin sheath lets the impulse leap between nodes of Ranvier → fast conduction.

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Drag the “Stimulus” slider on the right past threshold · press “Single stimulus” · pick a condition to see conduction change · click Anatomy / a part for details

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Membrane potential over time resting