Stem cells & Epigenetics · Cells & Genetics

STEM CELL SIMULATION

▸ Loading one shared genome for every cell…

▸ Building the differentiation tree (neuron · muscle · red cell · skin · liver · β)

▸ Calibrating the potency ladder (toti → pluri → multi)

▸ Loading epigenetic switches: DNA methylation & histones

▸ Starting Yamanaka reprogramming (iPSC)…

▸ Ready — Online. ✅

Potency level

🪜 Potency

Source type—

Differentiates into—

Genes ON—

Methylation—

Potency—

Viewing—

Note

Almost every cell in the body has the SAME genome. The difference between a neuron, a muscle cell, or a red blood cell lies in which genes are ON/OFF — controlled by epigenetics (DNA methylation & histone modification), WITHOUT changing the DNA sequence.

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Pick a "Scenario" (differentiation / same genome / epigenetics / reprogramming…) · click a cell type or concept for details

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Expression of 3 genes over differentiation time gene 1gene 2gene 3